Sirolimus is an immunosuppressive drug has been prescribed person receiving the organ donor transplant procedure. Also known as rapamycin, the drug is a derivative of bacterial species, Streptomyces hygroscopicus has been called. Sirolimus has been used to prevent organ rejection in people who undergo kidney transplant surgery most often. It is a long-term use.An after immunization, which is for drugs that suppress the immune system has a lower risk of renal toxicity, often they are used in preference to other immunosuppressive agents Masu. These drugs in his or her immune system has been specified for the person receiving the organ donor to ensure that you do not mount an attack might destroy the organ. The immune system attacks the donor organ donor organ because of differences in comparison to cells of the recipient cells. Sirolimus works by preventing the immune response to cytokine, called interleukin-2. Cytokines act as chemical signals to cells to provide an indication that the molecules of the immune system. Upset stomach, diarrhea, interleukin-2 - which is immune organs destroyed response.Possible sirolimus side effects, stomach, and may contribute to joint and back pain of T and B lymphocyte activation Constipation is an important cytokine is essential; vomiting, weight gain, hands, feet, swollen ankles and feet, difficulty falling asleep, fever and rash. These symptoms are usually temporary, can be a longer time. Please discuss them with anyone of his or her doctor to experience these symptoms. Bruising and bleeding of unknown causes severe symptoms, breathing difficulties, frequent urination, blurred vision, coughing include mood changes and an unusually fast or slow beat. If you have one or more of these symptoms, you need to speak with his or her doctor as soon as possible.